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I discuss informally, from a cost-benefit-informed perspective, the research up to 2015 on modafinil’s cognitive effects, the risks of side-effects and addiction/tolerance and law enforcement, and give a table of current grey-market suppliers and discuss how to order from them.

Modafinil is a wakefulness drug developed in the 1980s.

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So using adrafinil is inferior to using a straight dose of modafinil both because it stresses the liver (which apparently caused its discontinuation by the usual manufacturer) and because reportedly you need about 3 times more adrafinil to be metabolized into an equivalent dose of modafinil.

Its chief advantages were that all patents on it expired long ago, and it’s very rarely proscribed - so it was relatively cheap & easy to get.

Common side effects include diarrhea, constipation, headache, sleepiness, and itchiness.

Serious side effects include QT prolongation and severe allergic reaction.

It is typically used after trials of other drugs have failed.

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