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In this review we appraise what is known, and what is not known, about patterns of phosphorylation on the CTD of RNA polymerases II at the beginning, the middle, and the end of genes; the proposal that doubly phosphorylated repeats are present on elongating polymerase is explored.

We discuss briefly proteins known to associate with the phosphorylated CTD at the beginning and ends of genes; we explore in more detail proteins that are recruited to the body of genes, the diversity of their functions, and the potential consequences of tethering these functions to elongating RNA polymerase II.

Enzyme rates depend on solution conditions and substrate concentration.

Like other enzymes POLR2 has a saturation curve and a maximum velocity (V The mushroom poison has different effects on the each of the RNA Polyermases: I, II, III.

Isotope-filtered NMR experiments were collected by T.

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